Canada Meetings on Computer Aided Drug Designing and Drug Delivery September 27-28, 2019 Toronto, Canada

Track 1: Computer Aided Drug Designing

• Ligand and structure based drug design
• Computational Chemistry
• Molecular modelling
• Enzyme as target
• Receptor as target
• QSAR/QSPR Quantitative structure activity/property relationships    

Track 2 : Advances in Drug Delivery

• Novel Drug Delivery Systems
• Routes of Drug Administration
• Delivery of new therapeutic modalities
• Delivery of emerging biologics including mRNA, siRNA delivery, DNA delivery
• Vaccine Based Drug Delivery Technology

Track 3 : Drug Delivery Devices

• Needle-free delivery systems
• Patient centered integrated device implementation
• Devices development - continuous administration of drugs
• Human Factors, Behavioural Design And Human Centred Design For Delivery Device Development

Track  4 : Advancements in Drug Designing

• GPCR-Targeted Drug Design
• Lead Optimization for Drug Metabolism and Safety

Track 5: Novel Drug Discovery and Drug Delivery

• Role of computational biology
• Pioneering digital health and smart drug delivery systems
• Ligand binding studies
• Phage display technology for clinical application of protein drugs

Track 6: Large Molecule Drug Formulation

• Protein-Protein Interactions
• Inflammation and Autoimmune Inhibitors
• Kinase Inhibitor Chemistry
• Vaccines, Antibodies, Biotherapeutics
• Formulation development for biosimilars

Track 7: Bioanalysis and Stabilisation

• Bioanalytical development for large molecules
• Analytical development for novel therapeutics
• Analytical strategies for novel proteins and antibodies
• Stability testing and stability approaches for biologics
• Understanding the characterisation of large molecules
• Novel analytical tools to analyse particles

Track 8: ADME

• ADME (adsorption, distribution, metabolism and excretion)Of drugs
• Metabolism and toxicology
• Antiviral and antimicrobial activity
• Drug receptor interaction
• Kojic acid as a tyrosine inhibitor

Track 9:  Medicinal Chemistry and Drug Discovery

• Target discovery and validation
• Molecular modelling
• Drug receptor interactions
• Pro drug synthesis and drug targeting
• Toxicity, and therapeutic applications of antibiotics, antifungals, and antivirals

Track 10: Nanotechnology in Drug Delivery

• Nanoparticles that deliver three anti-cancer drugs to the lymph nodes
• Sustained drug delivery using a hydrogen
• Photosensitizing agent to enhance the ability of drug carrying nanoparticles
• Nanotechnology in Drug Delivery - Heart Disease
• Carbon nanofibers penetrate diseased cells
• Nanotechnology in Drug Delivery - Aging and other areas

Track 11:  Chem Virology

• Rapid Transmission
• ZIKV-Processing on the microfluidic cassette
• ZIKA virus infection may prevent reinfection
• Zika infection-A global threat to human population
• Major possible symptoms
•  Drugs and vaccines available so far

Track 12:  Posology

• Factors affecting the drug dosage
• Route of Administration

Track 13:  Cancer Studies: Drug Delivery Chemistry

• Magnetoelectric nanoparticles
• Nanoparticle drug delivery
• Problems of multidrug resistance in cancer therapies
• Taxoids as potent cytotoxic agents for tumour targeting drug delivery

Track 14: Drug Biotransformation and Disposition

• High resolution-mass spectrometry (HR-MS) technology
• Data-mining tools
• AB SCIEX TripleTOF™ 5600 System for the study of drug metabolism in BDC rats and CYP inhibition cocktail assays.

Track 15: Small Molecule Drug Formulation

• Recent progress in amorphous solid dispersions
• Advanced formulation strategies & methods for small molecules
• Overcoming key formulation challenges for small molecules
• Nano-formulations
• Quality-by-Design approaches
• Excipients for small molecule formulation

Track 16: Drug Delivery Systems

• Drug Delivery Technologies
• Drug Delivery Innovation

 Global Drug Discovery Market:

The global drug discovery market is expected to register a CAGR of approximately 8.0% during the forecast period, of 2018-2023. Due to the favourable regulatory framework by the governments in the region, North America dominates the market.

Rise in Technology Advancements and Innovations

In the recent past, drug discovery has evolved significantly with emerging technologies, helping the process to become more refined, accurate, and less time consuming. Due to automation, multi-detector readers, imaging hardware and software, high-throughput screening is one of the most widely used drug discovery technologies. There are several other evolving technologies, such as mass spectroscopy, protein and nucleic acid isolation, proteomics, RNAi, nanotechnology, and others, which contribute to advancements and innovations in drug discovery. The pharmaceutical and biotech companies are increasing their collaboration with contract development and manufacturing organizations, thus playing a crucial role in the development and innovation of new drugs.

Other factors contributing to the growth of this market are - rising prevalence of a wide range of diseases (such as cardiovascular and CNS-related disorders), rising healthcare expenditure, and upcoming patent expiration of blockbuster drugs.

Geographical Representation:

The global drug discovery market has been segmented by drug type, technology, service, end user, and geography. By geography, the market has been segmented into North America, Europe, Asia-Pacific, Middle East & Africa, and South America.

Geographically, North America is the most lucrative region in the market, due to the presence of a high number of top pharmaceutical and biotech companies in this region. The favorable regulatory framework and encouraging regulatory policies for investors to research and develop new drugs augment the growth of this market. Other factors, such as high-income population and healthy returns on investments for innovative technologies, are integral to the above factors. Asia-Pacific is expected to register a healthy growth rate, due to rising disposable incomes, economic growth, and increasing investment by the regional pharmaceutical and biotechnology industry.