20^th International Conference on Computer Aided Drug Designing and Drug Delivery September 24-25, 2018 Holiday Inn Chicago O’Hare Area 5615 North Cumberland Avenue, Chicago, IL 60631

WHO SHOULD ATTEND?

Heads, Directors, Group Leaders, Professors, Lecturers, Research Associates, Scientists, Investigators, Fellows, Readers from Pharmaceutical, Bio-pharmaceutical and Research Institutes working in,

Chemistry

Organic Chemistry

Translational Sciences/Medicines

Traditional Medicine

Pharmaceutical Sciences

Drug Delivery

Drug Designing

Drug Testing

Drug Discovery

Pharmacology

Food and Drug Administration

Natural Products Chemistry

Pharmacodynamics

Pharmacokinetics

Forensic Drug Chemistry

Antitargets and Drug Safety

Neurodegenerative Diseases

Personalised Medicines

Chemical Biology

Biomedical Sciences

The scientific program includes Keynote & Plenary Talks, Video Presentations, Poster Presentations and E-Posters. Furthermore, oral communications of (post)doctoral junior scientists will be considered. It is the goal of the organizers to make this meeting an event of scientific excellence, attractive to both industrial and academic scientists.

 

Track 1: Large Molecule Drug Formulation

• Protein-Protein Interactions

• Inflammation and Autoimmune Inhibitors
• Kinase Inhibitor Chemistry
• Vaccines, Antibodies, Biotherapeutics
• Formulation development for biosimilars

Track 2 : Advances in Drug Delivery

• Novel Drug Delivery Systems
• Routes of Drug Administration
• Delivery of new therapeutic modalities
• Delivery of emerging biologics including mRNA, siRNA delivery, DNA delivery
• Vaccine Based Drug Delivery Technology

Track 3 : Drug Delivery Devices

• Needle-free delivery systems
• Patient centered integrated device implementation
• Devices development - continuous administration of drugs
• Human Factors, Behavioural Design And Human Centred Design For Delivery Device Development

Track  4 : Advancements in Drug Designing

• GPCR-Targeted Drug Design
• Lead Optimization for Drug Metabolism and Safety

Track 5: Bioanalysis and Stabilisation

• Bioanalytical development for large molecules
• Analytical development for novel therapeutics
• Analytical strategies for novel proteins and antibodies
• Stability testing and stability approaches for biologics
• Understanding the characterisation of large molecules
• Novel analytical tools to analyse particles

Track 6: Computer Aided Drug Designing

• Ligand and structure based drug design
• Computational Chemistry
• Molecular modelling
• Enzyme as target
• Receptor as target
• QSAR/QSPR Quantitative structure activity/property relationships    

Track 7: ADME

• ADME (adsorption, distribution, metabolism and excretion)Of drugs
• Metabolism and toxicology
• Antiviral and antimicrobial activity
• Drug receptor interaction
• Kojic acid as a tyrosine inhibitor

Track 8:  Medicinal Chemistry and Drug Discovery

• Target discovery and validation
• Molecular modelling
• Drug receptor interactions
• Pro drug synthesis and drug targeting
• Toxicity, and therapeutic applications of antibiotics, antifungals, and antivirals

Track 9: Protein Biochemistry

• Protein role and importance
• Overcoming protein formulation challenges
• Proteins, Peptides, Biosimilars

Track 10:  Chem Virology

• Rapid Transmission
• ZIKV-Processing on the microfluidic cassette
• ZIKA virus infection may prevent reinfection
• Zika infection-A global threat to human population
• Major possible symptoms
•  Drugs and vaccines available so far

Track 11:  Pharmacology

• Principles of Pharmacology
• Psychopharmacology & Neuropharmacology
• Clinical Pharmacology
• Psychopharmacology & Neuropharmacology
• Ethnopharmacology
• Molecular and Cellular Pharmacology

Track 12:  Posology

• Factors affecting the drug dosage
• Route of Administration

Track 13: Novel Drug Discovery and Drug Delivery

• Role of computational biology
• Pioneering digital health and smart drug delivery systems
• Ligand binding studies
• Phage display technology for clinical application of protein drugs

Track 14: Nanotechnology in Drug Delivery

• Nanoparticles that deliver three anti-cancer drugs to the lymph nodes
• Sustained drug delivery using a hydrogen
• Photosensitizing agent to enhance the ability of drug carrying nanoparticles
• Nanotechnology in Drug Delivery - Heart Disease
• Carbon nanofibers penetrate diseased cells
• Nanotechnology in Drug Delivery - Aging and other areas

Track 15:  Cancer Studies: Drug Delivery Chemistry

• Magnetoelectric nanoparticles
• Nanoparticle drug delivery
• Problems of multidrug resistance in cancer therapies
• Taxoids as potent cytotoxic agents for tumour targeting drug delivery

Track 16: Drug Biotransformation and Disposition

• High resolution-mass spectrometry (HR-MS) technology
• Data-mining tools
• AB SCIEX TripleTOF™ 5600 System for the study of drug metabolism in BDC rats and CYP inhibition cocktail assays.

Track 17: Small Molecule Drug Formulation

• Recent progress in amorphous solid dispersions
• Advanced formulation strategies & methods for small molecules
• Overcoming key formulation challenges for small molecules
• Nano-formulations
• Quality-by-Design approaches
• Excipients for small molecule formulation

Track 18: Drug Delivery Systems

• Drug Delivery Technologies
• Drug Delivery Innovation

CADD & Drug Delivery 2018 conveys recent developments in Novel Drug Delivery Systems (NDDS), approaches in drug delivery systems and Challenges. Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue, cell or intracellular compartment, the control over release kinetics, the protection of the active agent or a combination of the above. Nanoparticles (NPs) were proposed as drug carriers over 30 years ago and have received growing attention since, mainly due to their stability, enhanced loading capabilities and control over physicochemical properties. The unique pathophysiology of solid tumors allows passive accumulation of NPs at these sites upon intravenous injection. Furthermore, stealth NPs with long circulation times is more efficient in reaching tumor tissue.

The global advanced drug delivery market should grow from roughly $178.8 billion in 2015 to nearly $227.3 billion by 2020, with a compound annual growth rate (CAGR) of 4.9%.

Importance & Scope:

CADD & Drug Delivery 2018  refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. This conference will discuss effective formulation and delivery technologies for enhancing solubility and drug delivery. CADD & Drug Delivery 2018 aims to aggregate leading experts from around the world who will discuss on formulation and delivery, and show how they are developing poorly soluble drugs into scientifically sound, patient-centric formulations, and reducing their product development timelines. It also provides the chance for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns, practical challenges encountered and the solutions adopted in the fields of Drug delivery.

CADD & Drug Delivery 2018  will showcase new and innovative technologies by renowned scientists. It benefits to pharmacological, researchers, professors, and companies. Conferences also benefits and share knowledge between scientist, doctors and delegates. Exchange of idea among companies and they share knowledge to each other about their product at the conference leading to lead to Public- private partnerships and collaborations. The university member attend conferences to know and share about what research has already been done and what research is going to be done in the area of drug delivery. We bring together business, creative, and technology leaders from the Drug Delivery industry for the most current and relevant.

Glance at Market of CADD & Drug Delivery 2018:

The global advanced drug delivery market should grow from roughly $178.8 billion in 2015 to nearly $227.3 billion by 2020, with a compound annual growth rate (CAGR) of 4.9%. Analyses of global market trends, with data from 2013, estimates for 2015, and projections of compound annual growth rates (CAGRs) to 2020

For 2015, Drug Delivery Global market reached $150.3 billion, according to BCC research. This was an increase from $142 billion the previous year. Given its predicted annual growth the market represents a considerable business opportunity, which has been reflected in the increasing number of drug delivery specialists.

Major Drug Chemistry Associations around the Globe

·      Controlled Release Society

·      Society for biomaterials

·      Washington State Pharmacy Association

·      Inhalation Drug Delivery Association

·      International society of drug delivery sciences and technology.

·      American Association of Pharmaceutical Scientists

·      Japanese Society of Drug Delivery Systems

·      Parenteral Drug Association

·      International Association for Pharmaceutical Technology

Top Universities: USA

·      Harvard University

·      Stanford University

·      University California

·      Massachusetts Inst Tech (MIT)

·      California Inst Tech

·      Princeton University

·      University Chicago

·      Yale University

·      Cornell University

·      University Pennsylvania

Global

·      University Oxford

·      Tokyo University

·      Kyoto University

·      Imperial College London

·      University British Columbia

·      Tech University Munich

·      University Paris 11

·      University Zurich

Top companies playing key roles in drug delivery

USA

·      Oncolytics Biotech

·      Bristol-Myers Squibb

·      GlaxoSmithKline

·      Bend Research

·      Pfizer

·      BioDelivery Sciences

Global

·      PolyActivaUnilife

·      Mati Therapeutics

·      Formac Pharmaceuticals

·      Battelle

·      Toxikon

·      Novartis

MedChem and TDD 2017, USA

Conference Series LLC Ltd, successfully organized 18th International Conference on Medicinal Chemistry & Targeted Drug Delivery during December 06-08, 2017 at Dallas, USA and received a great and fruitful response. Eminent Scientists, Researchers, Pharmacists, Industry Professionals and scholar students have made their resplendent presence and addressed the gathering.

The theme of the conference “Scientists Unlock Research: Riding Waves in Chemistry, Drug Discovery and Smart Drug Delivery.”

MedChem & TDD 2017 Organizing Committee would like to thank the Moderator of the conference, Ms. Olayide A. Arodola, University of KwaZulu-Natal, South Africa who contributed a lot to the smooth functioning of this event.

Conference Series LLC Ltd, would like to convey a great appreciation to following honorable guests and Keynote speakers. 

L. Mario Amzel, Johns Hopkins University, USA

Thorsten Nowak, C4X Discovery Holdings PLC., UK

Tatsuya Takagi, Osaka University, Japan

Victor Hruby, University of Arizona, USA

Concepción González-Bello, University of Santiago de Compostela, Spain

Carsten Detering, BioSolveIT Inc., USA

Jetze J. Tepe, Michigan State University

Marc Le Borgne, University Lyon 1, France

Mitsuji Yamashita, Shizuoka University, Japan

Very Special Thanks to our Exhibitors and Sponsors to have bestowed and their faith and invested in us to make this event a fruitful one. We hope you continue your support in our future endeavors. 

Conference Series LLC Ltd, also took the privilege of felicitating MedChem & CADD-2016 Organizing Committee, Editorial Board Members of Journal of Medicinal Chemistry,  Journal of Drug Designing and  Biochemistry & Pharmacology, Keynote Speakers, Chair and Co-Chairs and Moderator whose support made the conference a great success.